Although recent advances in understanding the pathophysiology, diagnosis, and clinical monitoring of patients with multiple sclerosis (MS) have significantly increased the ability to detect and manage its progression, clinicians continue to examine optimal ways to care for patients. It has been shown that a multidisciplinary team approach is the most effective and efficient way of treating and managing these patients through facilitating the coordination of services and continuity of care while avoiding duplication and fragmentation for the patient and family. From evaluation and initial diagnosis, to identifying the most effective courses of therapy, to managing side effects and complications, to formulating a long-term treatment plan for each patient, having a diverse team of medical professionals offers patients with MS the opportunity to have optimal, well-rounded care in all areas. By acknowledging the aspects of collaboration inherent in healthcare and striving to improve systems and skills, identification of best practices in multidisciplinary team-based care holds the potential to enhance patient outcomes.

The goal of this enduring activity is to improve treating clinicians’ care of patients with MS by enhancing their knowledge of the issues surrounding MS management and the importance of multidisciplinary communication and collaboration to improve outcomes.

This enduring case activity is designed to meet the educational needs of neurologists, primary care clinicians, neuroscience nurses, and managed care and specialty pharmacists. No prerequisites required.

After completing this activity, the participant will demonstrate the ability to:
  • ANALYZE the latest clinical and laboratory criteria for recognizing and diagnosing MS in order to incorporate this information into evidence based diagnostic strategies.
  • CONSTRUCT appropriate disease and symptom management strategies for patients with MS that utilize information from key studies evaluating the safety and efficacy of available agents.
  • DISCUSS the roles of all members of the healthcare team in order to optimize overall care for patients with MS.
The University of Tennessee College of Pharmacy, the CMSC, and NPA take responsibility for the content, quality, and scientific integrity of this CPE/CME/CNE activity.

Consortium of Multiple Sclerosis Centers
This activity has been planned and implemented in accordance with the Accreditation Council for Continuing Medical education (ACCME) through the joint of the Consortium of Multiple Sclerosis Centers (CMSC) and ASiM. The CMSC is accredited by the ACCME to provide continuing medical education for physicians.

The CMSC designates this activity for a maximum of 1.0 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Alternatives
Nurse Practitioner Alternatives is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s (ANCC) Commission on Accreditation.

This activity is awarded 1.0 contact hour of continuing nursing education for RNs and APNs.

University of Tennessee College of Pharmacy
acpe logo The University of Tennessee College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education (ACPE) to provide continuing education for pharmacists. Successful completion of this application-based program will provide a statement for 1.0 contact hour credit (0.10 CEU) and will be available at the completion of the activity. Successful completion includes participating in the activity, completing a self-assessment instrument with a score of at least 70%, and completing an evaluation instrument. If you score less than 70% on the self-assessment instrument, you will be allowed to complete the examination 2 more times. A statement of participation will be available online immediately following successful completion of the activity. ACPE Program Number: 0064-9999-14-204-H01-P.

Your CE credits will also be submitted electronically to NABP. Pharmacists or pharmacy technicians with questions regarding their NABP e-Profile or CPE Monitor should refer to the FAQ section on the NABP website ( or contact NABP Customer Service: or telephone 847-391-4406.

NABP e-PROFILE ID NUMBER: To receive credit for your participation in this course, all pharmacists must include their NABP e-Profile ID number, along with their date and month of birth at the end of the evaluation.

The estimated time to complete this activity: 60 minutes.

Release date: September 25, 2014.       Expiration date: June 1, 2015.

As an accredited provider by the ACPE, it is the policy of The University of Tennessee College of Pharmacy to require the disclosure of the existence of any significant financial interest or any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation.

As a provider approved by the ANCC, NPA requires all persons in a position to influence the content of an accredited activity to disclose the existence of financial relationships with industry.

As a provider approved by the ACCME, it is the policy of CMSC to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. The Steering Committee is required to disclose only those relationships that are relevant to their specific presentation.

The Steering Committee reported the following:

Jacquelyn Bainbridge, PharmD, FCCP
Skaggs School of Pharmacy and Pharmaceutical Sciences
Department of Clinical Pharmacy and Department of Neurology
University of Colorado Anschutz Medical Campus
Aurora, CO
Dr Bainbridge reports receiving grants/research support from NIH and UCB Pharma; and reports receiving honoraria from and serving as a speaker for Teva Neuroscience and UCB Pharma.

Marijean Buhse, PhD, RN, NP-C, MSCN
Adult Nurse Practitioner
South Shore Neurologic
Stony Brook School of Nursing
Stony Brook, NY
Dr Buhse reports serving as a consultant/formal advisor for activities for, receiving honoraria from, and serving as a speaker for Biogen Idec, Genzyme Corporation, Novartis, and Questcor Pharmaceuticals, Inc.

Donna Graves, MD
Assistant Professor
Department of Neurology and Neurotherapeutics, Pediatrics
UT Southwestern Medical Center
Dallas, TX
Dr Graves reports serving as a consultant/formal advisor of activities for Teva Neuroscience; and reports receiving honoraria from and serving as a speaker for Bayer AG, EMD Sorono, Inc, Pfizer Inc, and Teva Neuroscience.

June Halper, MSN, APN-C, MSCN, FAAN (Planner)
Ms Halper reports serving as a consultant to Biogen Idec on a non-CME research activity.

Laurie Scudder, DNP, NP (Nurse Planner)
Ms Scudder has no relevant financial relationships to disclose.

This content has been reviewed by a clinician who has disclosed no relevant financial relationships.

Except as noted above, the staff at CMSC, NPA, The University of Tennessee School of Pharmacy, and ASiM have disclosed no relevant financial relationships.

Note: This disclosure policy is reflective of and in compliance with the ACCME, ANCC, and ACPE.

In accordance with ACPE Criteria for Quality, the audience is advised that authors in this CPE activity may include reference(s) to unlabeled, unapproved, or investigational uses of therapeutic agents or biomedical devices. The authors will inform the reader of when they discuss or reference an unapproved, unlabeled, or investigational use of therapeutic agent or biomedical device.

The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of The University of Tennessee College of Pharmacy, NPA, and/or the CSMC name(s) implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects, before administering pharmacologic therapy to patients.

The accreditors and ASiM are committed to protecting the privacy of its members and customers. This Web site is maintained as an information resource and service for physicians, nurses, nurse practitioners, pharmacists, other health professionals, and the public. Your personal information is kept confidential when you participate in a CME/CNE/ACPE activity on this Web site. Your information will never be given to anyone outside; only the information necessary to provide you with the services that you request are collected.

A participant, sponsor, faculty member, or other individual wanting to file a grievance with respect to any aspect of an activity sponsored or cosponsored by The University of Tennessee College of Pharmacy may contact the Associate Dean for Continuing Education in writing at grievance will be reviewed and a response will be returned within 45 days of receiving the written statement. If not satisfied, an appeal to the Dean of the College of Pharmacy can be made for a second level review.

There is no fee for this educational activity.

The following is an interactive case simulation designed to help you gauge your basic knowledge of the topic and then direct you to areas you may need to focus on. It consists of 3 sections: a web-based unaccredited pre-assessment, an interactive case study, a CME/CNE/CPE post-assessment/activity evaluation. Successful completion of this activity includes completing all 3 sections with a score of at least 70% on the web-based post-assessment. If you score less than 70% on the post-assessment, you will be allowed to complete the examination 2 more times. A statement of credit will be available online immediately following successful completion of the activity.


Improving Outcomes for Patients with MS:
A Team-Based Approach to Care

Marijean Buhse, PhD, RN, NP-C, MSCN; Jacquelyn Bainbridge, PharmD, FCC; and Donna Graves, MD


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